The introduction of new and novel airspace users with limited operational data and high uncertainty into the aviation sector has necessitated the need to develop a uniform set of regulations tailored to each of their operations. National Aviation Authorities (NAAs) have recommended the adoption of a risk-based approach to the development of these regulations central to which is a Safety Risk Management Process (SRMP). In keeping with contemporary safety risk management practices, it is important to take the uncertainty associated with this approach into consideration. This paper will provide a high-level description of how the outputs from a safety assessment process can vary based on the level of uncertainty taken into consideration and show how this impacts the resulting compliance assessment and compliance finding decision-making processes. This research has the potential to significantly change how NAAs approach rule-making and compliance activities. It enables NAAs to account for uncertainty implicit to regulatory compliance assessment and compliance finding processes and provides NAAs with a systematic and objective means of making compliance findings based on compliance risk.