Thermoresponsive Nanohybrids for Tumor Imaging

We demonstrate the prospect of using thermoresponsive polymer capped gold nanosphere-cadmium telluride quantum dot (QD) nanohybrids for minimally invasive detection of cancerous tissue and for feedback control of tumor temperature in localized hyperthermia therapy conducted using gold nanorods, to minimize damage to the surrounding healthy tissue. Here, we use a generalized nonlocal optical response method based cavity quantum electrodynamical formalism and show that the enhancement of the Rayleigh scattering intensity of the nanohybrid over that of the isolated gold nanosphere follows an exponential scaling with varying nanohybrid centre separation distance, in the close vicinity of the QD resonance frequency, which makes them ideal candidates for a multitude of distance based sensing applications.