Hyperimmune bovine colostrum containing lipopolysaccharide antibodies (Imm124-E) increases the relative abundance of beneficial bacteria in mice

We fed mice a hyperimmune bovine colostrum solution rich in lipopolysaccharide antibodies from cows vaccinated against a number of ETEC. Mouse weights and consumption were recorded during the feeding protocol and anatomical measures were obtained at the end of the experiment. We conducted 16s amplicon sequencing to analyse bacteria from the caecum, colonic mucosa and faeces of mice to examine the onset and magnitude of changes to gut bacteria resulting from this treatment.