A method for the quantitative analysis of gaseous mixtures by online mass spectrometry

Online mass spectrometry is a widely used technique in tracking composition changes of gas mixture during the reaction. This paper reports a quantification analysis method of gas mixtures detected by an online mass spectrometry. In this analysis, a mass spectrum correction coefficient matrix is generated based on the calibration of mass spectrometry intensities of premixed calibration gas mixtures, and then the concentrations of gas components are calculated from this matrix by subtracting the interferences of other components with overlapped peaks. The accuracy of obtained results were verified by online gas chromatography in the meanwhile. The detailed error analysis was supplied in a separate supplement document. This method can be applied on the online detection of gas phase reactions with promising advantages to analysis of online gas chromatography, which is suitable for analysis of spectra overlaps (a given m/z signal contributed from two or multiple components) and kinetic studies.