Allosteric Ligands of the Glucagon-Like Peptide 1 Receptor (GLP-1R) Differentially Modulate Endogenous and Exogenous Peptide Responses in a Pathway-Selective Manner: Implications for Drug Screening

Koole, Cassandra; Wootten, Denise; Simms, Richard; Valant, Celine; Sridhar, Rohan; Woodman, Owen; Miller, Lawrence; Summers, Roger; Christopoulos, Arthur; Sexton, Patrick

Allosteric Ligands of the Glucagon-Like Peptide 1 Receptor (GLP-1R) Differentially Modulate Endogenous and Exogenous Peptide Responses in a Pathway-Selective Manner: Implications for Drug Screening

journal contribution

posted on 2024-11-02, 05:34 authored by Cassandra Koole, Denise Wootten, Richard Simms, Celine Valant, Rohan Sridhar, Owen Woodman, Lawrence Miller, Roger Summers, Arthur Christopoulos, Patrick Sexton

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1.
DOI - Is published in 10.1124/mol.110.065664
2.
ISSN - Is published in 0026895X

Journal

Molecular Pharmacology

Volume

78

Issue

3

Start page

456

End page

465

Total pages

10

Publisher

American Society Pharmacology Experimental Therapeutics

Place published

Bethesda

Language

English

Copyright

Former Identifier

2006022245

Esploro creation date

2020-06-22

Fedora creation date

2011-11-04

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Keywords

Activation Agonist Determinants Diabetic-Patients Functional Selectivity Identification In-Vitro Mice Muscarinic Acetylcholine-Receptors Pharmacology

Allosteric Ligands of the Glucagon-Like Peptide 1 Receptor (GLP-1R) Differentially Modulate Endogenous and Exogenous Peptide Responses in a Pathway-Selective Manner: Implications for Drug Screening

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