Inactivation of astrocytic glutamine synthetase by hydrogen peroxide requires iron

Fernandes, Samantha; Dringen, Ralf; Lawen, Alfons; Robinson, Stephen

Inactivation of astrocytic glutamine synthetase by hydrogen peroxide requires iron

journal contribution

posted on 2024-11-01, 12:06 authored by Samantha Fernandes, Ralf Dringen, Alfons Lawen, Stephen RobinsonStephen Robinson

The specific activity of brain glutamine synthetase (GS) is lowered in several neurodegenerative diseases that involve iron-mediated oxidative stress.

History

Journal

Neuroscience Letters

Volume

490

Issue

1

Start page

27

End page

30

Total pages

4

Publisher

Elsevier Ireland

Place published

Ireland

Language

English

Copyright

Former Identifier

2006038178

Esploro creation date

2020-06-22

Fedora creation date

2015-01-19

Usage metrics

Keywords

Fenton reaction Glutamate-ammonia ligase Iron chelator Oxidative stress Primary astrocyte culture

Inactivation of astrocytic glutamine synthetase by hydrogen peroxide requires iron

History

Journal

Volume

Issue

Start page

End page

Total pages

Publisher

Place published

Language

Copyright

Former Identifier

Esploro creation date

Fedora creation date

Usage metrics

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Keywords

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