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Macrolactam analogues of macrolide natural products

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journal contribution
posted on 2024-11-23, 10:20 authored by Helmut Hugel, Andrew Smith, M Rizzacasa
The chemical modification of macrolide natural products into aza- or lactam analogues is a strategy employed to improve their metabolic stability and biological activity. The methods for the synthesis of several lactam analogues of macrolide natural products are highlighted and aspects of their biological properties presented.

History

Journal

Organic and Biomolecular Chemistry

Volume

14

Issue

48

Start page

11301

End page

11316

Total pages

16

Publisher

Royal Society of Chemistry

Place published

United Kingdom

Language

English

Copyright

This journal is © The Royal Society of Chemistry 2016

Former Identifier

2006074308

Esploro creation date

2020-06-22

Fedora creation date

2017-06-15

Open access

  • Yes