Numerical simulation of the fluid dynamics in vitreous cavity due to saccadic eye movement

In this study, the flow dynamics of vitreous due to saccadic movements following vitreous liquefaction or in post-vitrectomy eyes is investigated. Using a dynamic mesh technique, the eye motion was modeled and unsteady three-dimensional forms of continuity and Navier¿Stokes equations were solved numerically. Firstly, the numerical model was validated for a sphere as a model of vitreous chamber and agrees well with the results based on available analytic solutions and experimental data. Then, numerical simulation was performed based on a deformed sphere with an indentation representing the lens. This consists of a vitreous cavity filled with a liquid having the viscosity of liquefied vitreous and balanced salt solution. The wall shear stress on the retina was computed and compared for various saccade amplitudes.