<p dir="ltr">A recent re-emergence of the Chandipura virus (CHPV) has been documented in Gujarat, India, echoing the outbreak that occurred two decades earlier in Andhra Pradesh, Maharashtra, and Gujarat. As of July 31, 2024, 148 cases of Acute Encephalitis Syndrome (AES) have been reported in India, with 140 cases across 24 districts in Gujarat. The virus has also spread to Madhya Pradesh (n = 4), Rajasthan (n = 3), and Maharashtra (n = 1). Among the 148 AES cases, 51 have been confirmed as CHPV infections, resulting in 59 deaths.</p>