The current implementation of Factories of the Future Public-Private-Projects under Framework 7 protocols in the European Union, is used as a case Study in the potential for paradigmatic change in the industrial manufacturing sector. A Re-reengineering approach is outlined in which a new Competitive Adaptability 5-Influences Analysis approach under conditions of collaborative alliance is described as an alternative to Porters 5-Forces Competitive Rivalry Analysis model, and a generic approach is described to identifying new critical success factors in Blue Ocean style strategic re-positioning. These approaches represent the onset of a new collaborative-adaptability paradigm for future approaches to the re-development, re-structure and re-enervation of the European industrial manufacturing sector and its potential influence on agility in global manufacturing. Organizational adaptation and transformative change management in technology-based organizations are explored in the context of collaborative alliances.