The nitroxyl anion (HNO) is a potent dilator of rat coronary vasculature

The nitroxyl anion (HNO) is the one-electron reduction product of NO·. This redox variant has been shown to be endogenously produced and to have effects that are pharmacologically distinct from NO·. This study investigates the vasodilator and chronotropic effects of HNO in the rat isolated coronary vasculature.